Intra Uterine Insemination
Ovulation induction is done with oral drugs with or without injections (hormones) depending upon the woman’s ovulation status.
IUI is planned after ovulation induction with HCG injection. Husband’s sperm count should be at least 10 millions, preferably above 20 millions. The success opportunities are 18 – 25 %. Minimum investigations required before IUI being – Tube test for wife and semen analysis for the husband along with the basal blood investigations.
Donor insemination is done using cryo preserved sperms, as per ICMR guidelines after thorugh blood analysis on three occasions for the donor with adequate quarantine period of 6 – 9 months. Couples can choose the phenotypical features stored in computers about Donors.
Sperm counts – 100% motile are available after specific sperm preparation methods for AID – Artificial Insemination Donor.
When is IUI used?
IUI is a fertility treatment often selected by couples who have been trying to conceive for at least one year with no success. IUI may be selected as a fertility treatment with any of the following conditions:
- Unexplained infertility
- Low sperm count
- Decreased sperm mobility
- Requirement of donor sperm
- A hostile cervical condition, such as cervical mucus that is too thick
- Cervical scar tissue from past procedures or endometriosis
- Ejaculation dysfunction
IUI provides the sperm an advantage being kept nearer to the place of fertilization, but still requires a sperm to reach and fertilize the egg on its own.
The IUI procedure is simple and may be performed even if the woman is not receiving medication to improve her egg production. Many physicians will encourage women to take medications to stimulate the ovaries to increase egg production in order to improve the chance of achieving pregnancy. An ultrasound will be used to monitor the size of the follicles (follicles harbors maturing eggs inside) .The hormone, human Chorionic Gonadotropin (hCG), is administered to stimulate the release of eggs from the follicles.
A semen sample will be washed by the lab staffs and they separate the sperms from the seminal fluid. There are many types of procedures depending on the numbers of sperms in the sample provided by the husband. A catheter is used to inject the processed sperm directly into the uterus. This process maximizes the number of sperm cells that are placed in the uterus, thus increasing the possibility of conception. The IUI procedure takes little time and involves minimal discomfort. The next step is to watch for signs and symptoms of pregnancy.